Hospital-onset Clostridium difficile infection rates in persons with cancer or hematopoietic stem cell transplant: a C3IC network report.

Risk factors for recurrent Clostridium difficile infection in hematopoietic stem cell transplant recipients.

BACKGROUND Recurrent Clostridium difficile infection (CDI) represents a significant burden on the healthcare system and is associated with poor outcomes in hematopoietic stem cell transplant (HSCT) patients. Data are limited evaluating recurrence rates and risk factors for recurrence in HSCT patients. METHODS HSCT patients who developed CDI between January 2010 and December 2012 were divided ...

Risk factors for healthcare-associated Clostridium difficile infection in pediatric hematopoietic stem cell transplant recipients

1305. External validation of predictive scores for mortality following Clostridium difficile infection Catherine Beauregard-Paultre, MD; Claire Nour Abou Chakra, PhD; Allison Mcgeer, MD, MSc; Annie-Claude Labbé, MD; Andrew E. Simor, MD, FRCPC, FACP; Wayne Gold, MD; Matthew P. Muller, MD, PhD, FRCPC; Jeff Powis, MD, MSc, FRCPC; Kevin Katz, MD, CM, MSc, FRCPC; Suzanne Cadarette, PhD; Jacques Pépi...

Early Clostridium difficile Infection during Allogeneic Hematopoietic Stem Cell Transplantation

Clostridium difficile infection (CDI) is frequently diagnosed in recipients of allogeneic hematopoietic stem cell transplantation (allo-HSCT). We characterized early-transplant CDI and its associations, and analyzed serially-collected feces to determine intestinal carriage of toxigenic C. difficile. Fecal specimens were collected longitudinally from 94 patients during allo-HSCT hospitalization,...

Clostridium difficile Infection in Solid Organ and Haematopoietic Stem Cell Transplant Recipients

Patients undergoing solid organ and stem cell transplantation are at increased risk of Clostridium difficile infection (CDI) compared with nontransplant patients. CDI may be associated with significant morbidity in this population including prolonged hospitalization, increased hospital charges, and complications in the transplanted organ. A combination of host factors, including both B-cell and...

Clostridium difficile Infection in Hematopoietic Stem Cell Transplant Patients: A Single-center Experience